Now I am really afraid to stay on Eliquis....today was an eye opener February 05, 2019 04:47AM |
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tobherd
Do you know the name of the reversal agent, Carey? I believe they used one, but said it wasn't all that effective.
I'm back to the hospital now to see what his status is. I do think this whole thing warrants more discussion - at least for me it does. I have NO interest in warfarin, but I do have an interest in getting off blood thinners all together, since I no longer have Afib and my TEE's were good...
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katesshadow
Shouldn't anyone who has Afib have an automatic "1" on the CHADS score?
Re: Now I am really afraid to stay on Eliquis....today was an eye opener February 06, 2019 02:53PM |
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katesshadow
Shouldn't anyone who has Afib have an automatic "1" on the CHADS score?
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PBqltbook
Now I'm confused. When did "female" get dropped from the factor list?
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smackman
Why is Eliquis $415 a month in the USA but approx. $130 in Canada
Re: Now I am really afraid to stay on Eliquis....today was an eye opener February 06, 2019 04:58PM |
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Carey
Why is Eliquis $415 a month in the USA but approx. $130 in Canada
Ask Congress why they prohibited Medicare from negotiating drug prices and you'll have the answer.
Meanwhile, you can get Eliquis for $165 per month from planetdrugsdirect.com. Completely legit and reputable. I've used them for a couple of years.
Re: Now I am really afraid to stay on Eliquis....today was an eye opener February 06, 2019 05:14PM |
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I know you are joking when you say ask Congress. Maybe I will ask them to explain their luxurious life style on there salary and living in one of the most expensive cities in the US plus living in Mansions with walls and armed personnel by their side.Quote
Carey
Why is Eliquis $415 a month in the USA but approx. $130 in Canada
Ask Congress why they prohibited Medicare from negotiating drug prices and you'll have the answer.
Meanwhile, you can get Eliquis for $165 per month from planetdrugsdirect.com. Completely legit and reputable. I've used them for a couple of years.
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smackman
How is the Chads score figured with someone like me? I have minimal high blood pressure issues(like 125/78 taking 25 mg of ER Metoprolol 1 time a day).
No AFIB issues since last Ablation in June 2016
61 years old
1 stent put in Jan 2012.
Great flow velocity after LAA was isolated according to TEE in December 2016 BUT NO A WAVE DETECTED.
Can a Chad’s score be accurately figured on Cases like mine?
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Catherine
...besides, why would any drug company release a life altering/threatening medication first then years later an antidote? Greed?
FDA approved Eliquis in 2012;
Andrexxa, the antidote, approved in 2018. Really?
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Catherine
Carey, go back and read the OP’s post and stop inserting your script into what YOU think has happened to him.
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I don’t appreciate your accusing me of “fear mongering” and censoring the forum. Instead, I would have hoped you would have addressed some of the points I made; for example, you bandy about the positive research and data, etc. on a drug that is comparatively new, and you express no concern about it being dispensed without an antidote.
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I might have mentioned, in a past post, when my husband was hospitalized after valve replacement surgery, the gentleman in the next bed was bleeding internally and for fwo days his doctors were unable to find the source. He was scheduled for exploratory surgery the next morning. He was on Xarelto and they had no antidote.
Re: Now I am really afraid to stay on Eliquis....today was an eye opener February 08, 2019 02:22AM |
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Elizabeth
Anticoagulants do not cause bleeding. -------
Once bleeding starts anticoagulants promotes it.
Re: Now I am really afraid to stay on Eliquis....today was an eye opener February 08, 2019 12:53PM |
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GaryPNW
One additional comment on risk of blood clots with Afib. On the question of, does someone with controlled afib need to be on an anticoagulant, my EP replied that at that time (about 3 years ago) studies had not been able to show a statistical difference in the risk of clotting between controlled and uncontrolled populations.
Re: Now I am really afraid to stay on Eliquis....today was an eye opener February 08, 2019 06:46PM |
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tobherd
Not sure if I posted here on this or not...but Dr. Natale's assistant said that they don't use the CHAD score anymore to determine whether or not to take you off the Eliquis - they use the TEE.
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Re: Now I am really afraid to stay on Eliquis....today was an eye opener February 10, 2019 08:01PM |
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safib
One additional comment on risk of blood clots with Afib. On the question of, does someone with controlled afib need to be on an anticoagulant, my EP replied that at that time (about 3 years ago) studies had not been able to show a statistical difference in the risk of clotting between controlled and uncontrolled populations.
That's why CHADs doesn't differentiate, it applies to Afib whether controlled or not. So your EP statement in no way negates the evidence for use of anticoagulant with Afib.
What does it mean to be controlled in this context, did you ask him/her? Controlled as in duration and frequency? Controlled as in having TEE with certain results?
There are recent studies which are attempting to assess risk with stratified Afib. Until that's done, self-supplementing as an alternative to NOACs because of some parameter like elevated blood viscosity (even if it could be reliably and repeatably measured) and/or your perception of how controlled your Afib is completely lacks evidence compared to CHADs or TEE. With regard to the latter, I have confidence Natale has the evidence to support his approach.
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wolfpack
Probably because aspirin is useful in cases where platelets encounter anything other than smooth endothelium, like stents or an occlusion device.
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bettylou4488
so reading thru the comments because I really want to take ibuprofen for this potential kidney stone or whatever pain it is. (appt w/ urologist tomorrow.) I take xeralto but looking at that scoring thing as i understand it.. If you have or had afib that is factored in. The female part was taken out. So i don't need to count that. But i do have high BP. So that is just 1 point? Not 2 (for the female part). None of the other factors seem to fit for me. I did have some problems when i was on metrop (and had to take 3 days of lasix) but i truly think that was the drug b/c i am fine now. My BNP blood test went down way below normal. Plus outside even the kidney stone issue- do i NEED to take this for a YEAR (at least?) i have 2 friends who have afib.. one is on dofetilide (like me) and went in the hospital to get on it- and did not go home on any blood thinner. THe other friend goes in and out. She takes solotel PIP and elaquis for a few days after.. then stops both. Is there an SOP?
Re: Now I am really afraid to stay on Eliquis....today was an eye opener February 12, 2019 12:00AM |
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bettylou4488
do i NEED to take this for a YEAR (at least?)
Re: Now I am really afraid to stay on Eliquis....today was an eye opener February 13, 2019 05:04PM |
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Elizabeth
The article said that 20% of all strokes are because of AF, so what is the 80% due to?
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alxndr01
I was emailing with a guy in New Zealand and he was paying $30 a month for Eliquis. The high prices in the U.S. are to take up the slack from those really inexpensive costs in other countries.
I've looked into the comments of many people who are taking Eliquis. Most of them don't like it. Like many things you mainly hear from the people who tend to get relatively positive results. You rarely hear from the people having problems after the drug gets into the public.
[ethicalnag.org]
Check this out. They're already in the 2nd stage trials.
[www.prnewswire.com]
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Carey
The article said that 20% of all strokes are because of AF, so what is the 80% due to?
All those other things the CHADS-Vasc score measures.
.
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Dean
The vast majority of afibbers on this forum have drastically altered their eating habits and lifestyles for the better so vastly diminishing their risk of stroke from all causes.
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Carey
The vast majority of afibbers on this forum have drastically altered their eating habits and lifestyles for the better so vastly diminishing their risk of stroke from all causes.
They have? Not sure if that's true and how you would know it, but even if it is true, what's the stroke rate for people on this forum?
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colindo
Well Carry,
If you change your life style, cut out alcohol, reduce weight, lower blood pressure, eat low carb, get off the couch etc.
You will reduce your afib load and change your CHAD score to a point where you won't need any blood thinners which will stop its calcification action.
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colindo
Well Carry,
If you change your life style, cut out alcohol, reduce weight, lower blood pressure, eat low carb, get off the couch etc.
You will reduce your afib load and change your CHAD score to a point where you won't need any blood thinners which will stop its calcification action.
A better alteritive then would be nattokinase or Natto as well. It's at least thinning my blood and has lowered my figrinogen level, it's also making my finger and toe nails grow faster. Which means that calcium which does the damage to your artries and causes strokes is now going where it belongs, to my bones.
Some more info for you Carry.
Natto. There isn't pill like it
NATTO ADVANTAGES, the wonder food.
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colindo
Nattokinase. I wonder if there was money to be made from it, would we see evidence of its effectiveness?
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safib
Well Carry,
If you change your life style, cut out alcohol, reduce weight, lower blood pressure, eat low carb, get off the couch etc.
You will reduce your afib load and change your CHAD score to a point where you won't need any blood thinners which will stop its calcification action.
A better alteritive then would be nattokinase or Natto as well. It's at least thinning my blood and has lowered my figrinogen level, it's also making my finger and toe nails grow faster. Which means that calcium which does the damage to your artries and causes strokes is now going where it belongs, to my bones.
Some more info for you Carry.
Natto. There isn't pill like it
NATTO ADVANTAGES, the wonder food.
So you are advocating ignoring CHADs and not taking prescribed anticoagulants, and instead proceeding with trying to lower CHADs enough that eventually you no longer need to take anticoagulants (according to CHADs!). You then follow this by the natto (miracle drug). The problem with your plan is there is no rigorous validation of any of it. In addition, there is plenty of risk in the interim while you are trying to reduce CHADs, if you can do it at all. This in addition to the unknown safety and dosing and efficacy data for natto.
These kinds of approaches which go against the best evidenced-based medical opinion are ill-informed and potentially dangerous.
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colindo
If you have a CHADs score of 2 you have a 2% chance of a stroke, then if you take a blood thinner you have a 3% chance of a blood bleed.
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colindo
Never the less 98% chance of not having a stroke are good odds. No one is going to guarantee blood thinners is going to improve those odds much.
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Carey
This whole theory that afib is a lifestyle disease is a crock, in my opinion. Lifestyle can influence it and make it better or worse, but it's not a cause.
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wolfpack
This whole theory that afib is a lifestyle disease is a crock, in my opinion. Lifestyle can influence it and make it better or worse, but it's not a cause.
I concur.
I got AF at 6’0”, 170 lb, BP 115/70, running 35 miles/wk, eating a zero-fat diet and, of course, not smoking. What was I supposed to do to rend the “Scarlet AF” from my chest?
My dad got AF at age 50. My mom at age 71. Hmmm...
If poor diet and holding down sofas from the deleterious effects of anti-gravity were the sole cause of AF, it’d be a lot more prevalent than 5% of the population!
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colindo
So telling forum members that lifestyle changs is a crock is not good advise. BTW not all afibbers are like yourself and Carey.
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colindo
So telling forum members that lifestyle changs is a crock is not good advise.
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colindo
Safib, you assume an ablation is an option for all of us.
I also dont believe your stroke risk goes up yearly, and thats my opinion. Which used to be allowed on this forum.
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safib
Safib, you assume an ablation is an option for all of us.
I also dont believe your stroke risk goes up yearly, and thats my opinion. Which used to be allowed on this forum.
It is not that your annual stroke risk goes up, it's that your cumulative stroke risk goes up (cumulative meaning your risk over a period of several years). The simplest model to explain this is coin flipping with a fair coin. The probability of getting a head in one flip is 0.5. For n flips it is 1 - (1 - 0.5)^n. So the probability of getting a head in n = 2 flips is 0.75 , and the probability of getting a head in n = 10 flips is .999. If you employ the same model for stroke, where the annual stroke risk is 2%, then the cumulative stroke risk is 18.3% over 10 years. Now there are issues with the model, but it is a good choice lacking long term longitudinal data . Better models would account for some fine tuning to allow for stroke incidence occurring continuously rather than once per year, or time variation of the stroke risk, or dependency of stroke events (having one stroke would make it more likely to have another). But it wouldn't change the results much. This isn't opinion, cumulative risks go up with time and models like this are well-validated.
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colindo
And I ask why, why is my stroke risk after 10 years now 18.3%, what has caused that.? Is it my lifestyle, maybe?
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Carey
And I ask why, why is my stroke risk after 10 years now 18.3%, what has caused that.? Is it my lifestyle, maybe?
Your risk didn't change. What happened is math.
Stroke risk is usually stated as risk per year. So if your risk of having a stroke in one year is 2%, over the course of 10 years you incur that 2% risk 10 times. As safib explained, that risk adds up. It's not 20% because it's not simple addition, but it does add up. The answer is the risk is 18.3% that you'll have at least one stroke in a 10 year period.
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colindo
And I ask why, why is my stroke risk after 10 years now 18.3%, what has caused that.? Is it my lifestyle, maybe?
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colindo
Will blood thinners stop that one stroke in 10 years?
As I said my sister is now in hospital with a stroke after being on thinners for 12 months, that is in fact true.
Re: Now I am really afraid to stay on Eliquis....today was an eye opener March 04, 2019 09:26PM |
Registered: 7 years ago Posts: 541 |
Quote
Carey
do i NEED to take this for a YEAR (at least?)
What's your afib situation? Are you having episodes? If not, when was the last one? You say you're a CHADs-Vasc 1, so that means anticoagulants are a judgement call. The biggest factor in that decision is going to be afib activity.
The other question is how long do you expect to need ibuprofen? It's not that ibuprofen is completely contraindicated; it's just that it shouldn't be taken with anticoagulants long term. I've been told by two EPs that taking it for a few days is okay, but a few weeks is not.
And, really, if it's not going to be long term, I'd go for the Norco. You won't become addicted in a few days or even weeks, and with kidney stones you might need a lot more than ibuprofen. I've seen people passing kidney stones who were in horrible pain even with morphine.
Re: Now I am really afraid to stay on Eliquis....today was an eye opener March 15, 2019 11:38AM |
Registered: 5 years ago Posts: 8 |