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Marco, how long do your episodes take to convert on their own? I ask because my philosophy has always been to limit my time in afib as much as possible as "afib begets afib." Certainly these rhythm meds can cause arrhythmia, I had a call with a member yesterday who had read my posts of lowering my PIP dose as I'd been seeing what appears to be conversion from afib to a flutteby GeorgeN - AFIBBERS FORUM
QuoteYuxi Are you not concerned with the risk of 1:1 conduction atrial flutter? I actually spend and have spent most of my time in afib being quiet. I recall EP, columnist and blogger, Dr. John Mandrola wrote about going into afib and taking PIP flec. He's a cyclocross rider and had gone into afib during a ride. This was maybe 10 or more years ago and he wrote that being quiet reduced yby GeorgeN - AFIBBERS FORUM
QuoteYuxi Hi George, what's your typical heart rate when in an Afib episode? I am assuming not very high and you are not very symptomatic? If I don't do anything, I'd say an average in the 130's - 140's (based on beat to beat data from a Polar H10 strap and collected by the Heart Rate Variability Logger app). With breathwork, inversions, standing on my head or the likeby GeorgeN - AFIBBERS FORUM
QuoteMarco thanks G. I'm assuming you are taking Iodine, if so how much are you taking? 50 mg of Lugol's liquid iodine. If anyone decides to pursue this, please don't just start taking iodine without informing yourself completely about iodine protocols. There can be serious consequences if a protocol is not followed. One issue is that iodine is a halide as is bromine. The iodiby GeorgeN - AFIBBERS FORUM
QuoteMarco I have seen in some older posts that Flecainide contains Fluoride, is that still the case as today? does Propapenone contain Fluoride as well? Other than the Fluoride that I would prefer to avoid, being paroxysmal afibber, would one be better than the other one? Propafenone: C21H27NO3 Flecainide: C17H20F6N2O3 Here is the 2004 paper about PIP flecainide & propafenone. Reby GeorgeN - AFIBBERS FORUM
Quotebettylou4488 along with CBT-I. I tried CBT-I with a coach last fall. They said they had 95% success. I failed. At least for me, the idea was to compress your sleep window, and once your brain adapted and you were sleeping well, increase your window. All I got was a lot less sleep, to the point driving was dangerous. My coach had me try other things, and increase the sleeping window.by GeorgeN - AFIBBERS FORUM
QuoteCarey It seems the US military might do just that. I can't find the study now, but several years ago I read about a study commissioned by the US military. As you might imagine, they hold huge stockpiles of vital medications, and those stockpiles have to be rotated periodically to account for expirations, and that's extremely expensive. So the study they commissioned looked into howby GeorgeN - AFIBBERS FORUM
QuoteKleinkp I have 6 month supply of eliquis from 2021. I know label suggest it has shelf life. But can I use it if needed in future? Stored in temp controlled closet with my other meds stock pile. Here is a story from 2017 on meds generally. Have no idea how stable Eliquis is. In my own experiment from taking 8 year expired (and also blister packed) flecainide (posted here), I'm gueby GeorgeN - AFIBBERS FORUM
I've used goldpharma.com for probably at least 15 years. They are a broker for pharmacies in Europe. I've used them to purchase branded, blister packed, flecainide (Tambocor - only generic is sold in the US from what I've seen) as well as some meds used off label for my son with brain cancer as Susan noted. This was for part of an experimental protocol (he's still alive atby GeorgeN - AFIBBERS FORUM
Hi Larry, Perhaps not consuming 90 minutes (I made that up - figure out what works best for you) before/after eating?by GeorgeN - AFIBBERS FORUM
QuoteGeorgeN I recently got a friend (with his EP's approval) to drop his chronic flec dose to 75 bid from 100 bid. He may now (after consulting with his EP) try 50 bid. If a med is working, I don't think most docs give a lot of consideration to finding the minimum effective dose. Just talked to my friend I mentioned above in the quoted post, he has successfully dropped his dose toby GeorgeN - AFIBBERS FORUM
"The BPC 157 therapy as antiarrhythmic agent follows the evidence that NO is commonly proposed as an endogenous cardioprotectant antifibrillatory factor [64,65] and that BPC 157 might modulate NO-effects (for review, see, i.e., [60]), and thereby might have a consistently strong beneficial effect against various arrhythmias and various agents and procedures that might produce arrhythmias&quoby GeorgeN - AFIBBERS FORUM
QuotePixie When flecainide stopped working for me, my doctor ordered the following test for me to see if my flecainide dose could be raised. The lab was performed at Quest Diagnostics. FLECAINIDE (TAMBOCOR) Your Value 1.13 mcg/mL Standard Range 0.20 - 0.99 mcg/mL Since my value was higher than the range, she did not raise the dose. Generally the trough (lowest level during thby GeorgeN - AFIBBERS FORUM
QuoteDaisy But don’t assume your doctor will do this test or even be WILLING to do this test! As I posted here, I figured out from inadvertently taking a PIP dose of expired flec that my 300 mg dose of flec was too high. My hypothesis was that the expired flec had lost around 1/3 of its potency. The experiment I wanted to run was to consume 300 mg of the expired flec, then get my serum levelby GeorgeN - AFIBBERS FORUM
I concur with Carey. My daughter's father-in-law was diagnosed with afib & heart failure recently. At the beginning of July she and her family went to visit. He had an episode where he wasn't really "there" for a period of time ( 20-30 seconds ) . His BP was very low, but I don't recall the systolic ( maybe 60's ), the diastolic was in the very low 40's.by GeorgeN - AFIBBERS FORUM
QuoteMarco In the present study, the therapy effects and partly mechanisms were investigated. AF animal model was established by intravenous administered with the mixture of acetylcholine (Ach) and CaCl2 (66 μg/mL + 10 mg/mL) (i.v.) for 7 days. The actions of taurine (99 mg/kg∙d, introgastric administration) on the levels of Hs-CRP, IL-6, TNF-α, MMP-9, AngII, the extent of the fibrosis and ultrasby GeorgeN - AFIBBERS FORUM
Quotesusan.d Flecainide is not a drug one should experiment dosage with based on “how you feel your heart will behave”. By then it could potentially be a fatal mistake. There are dosage guidelines for a reason. Flecainide is a black box drug. Sure, but experimenting with a lower dose is a whole different thing than on the high side. I recently got a friend (with his EP's approval) to droby GeorgeN - AFIBBERS FORUM
Quotemjamesone That said, even ep's can differ interpreting some single leads. I've shown the same Kardia single lead to four ep's and got determinations of aflutter, SVT and afib! So sometimes it's as much of an art as anything else. Quotegloaming Yikes. I would think that an ECG readout would be highly definitive...albeit with variance due to conductance, the machine, theby GeorgeN - AFIBBERS FORUM
QuotePavanPharter Even ApoB and LPa can be ignored. I can manipulate either through diet and have done so. Curious what you've done to manipulate Lp(a)?by GeorgeN - AFIBBERS FORUM
QuoteMark It is my understanding that Kardia will not give you are reading of “aFib ” but will only give you a reading of “possible aFib.” Maybe not a technically important distinction and one made for liability issues or whatever but one that is still made—I think. Maybe the subscription model makes a definitive statement of “aFib”vs possible “aFib.” I don’t know. Is it then fair to say thatby GeorgeN - AFIBBERS FORUM
Does Natale's team have suggestions on docs they've worked with locally or relatively close to you that have done what they request?by GeorgeN - AFIBBERS FORUM
You can have a low afib heart rate - in the 80's or lower. I don't know what the maze might do to the ECG. Generally NSR should have a "p" wave. On a Kardia, a "Lead II" presentation has a better shot at showing a p wave. Basically hold the Kardia with your right thumb on the contact and put the left contact on a lower part of the left side of your body. I tby GeorgeN - AFIBBERS FORUM
QuoteSunshine13 I was wondering if you all can share what has worked for you. It is interesting. In many emergency departments, IV mag is used to convert afib in patients. It was used this way for a friend's 90 year old mother. One of my climbing partners is an emergency MD and I've chatted with him about this. He confirmed they used magnesium (usually as sulfate in the IV) in thiby GeorgeN - AFIBBERS FORUM
Quotealfrae13 I have afib episodes every couple of days. At that point I take 100mg flecainide and go back to NSR within a few hours. I read in a recent post that that individual was told by his doctor to wait several hours to see if it converts and only then take the medication. Any thoughts? 1. Have you successfully converted on your own in the past? If so how long did it take to convert? Iby GeorgeN - AFIBBERS FORUM
Mel-O It really kind of depends on how frequent the PAC's are. In this file are a lot of heart rate vs time graphs (NOT ECG's) that a member from the UK sent me years ago. I'll try to visually show what Carey is saying. In this graph, there are many PAC's (which show as fast beats) and most are followed by slow beats or compensatory beats. These are actually norby GeorgeN - AFIBBERS FORUM
QuoteMarco I just wanted to make a comment on study n2, the last at the bottom. Quintile n.5, the group who took the more marine omega 3 and had more Afib episodes, also took more alcohol and it was the group who also had the higher blood pressure, unless I'm not reading the study properly. . In the study, they said they adjusted for BP & alcohol. Here are my issues: 1. The basby GeorgeN - AFIBBERS FORUM
I posted this a few weeks ago on the omega 3 topic. I was a vegan when I had my first episode in 2004 (no longer vegan as of 2008 or 09). In 2015, I was tested for the first time for omega 3 index it was very low, around 3.something. Because of AlzD genetic risk, my doc wanted my omega 3 index between 10 & 12. Subsequently, I've run it generally north of 12 and as high as 19 without aby GeorgeN - AFIBBERS FORUM
QuotePavanPharter Another view - Pavan, an administrative thought. Why start a new thread? I say this as when you do, it pushes an older topic off the first page and out of view. Just post it as a reply in this thread would be my suggestion.by GeorgeN - AFIBBERS FORUM
Great news! Here is to this continuing!by GeorgeN - AFIBBERS FORUM
QuotePavanPharter Anyone here ever experience this? I did once as part of an AF episode. I recall this from years ago here: "The violent movement and stretching of the atria and ventricles caused by the fibrillation result in the release of ANP and BNP. These hormones immediately start dumping Na+ and water through the kidneys causing the “big pee” and normalizing the Na+/K+ ratio. ANP pby GeorgeN - AFIBBERS FORUM